产品货号:
Z39487
中文名称:
RIPK1抗体
英文名称:
Anti-RIPK1 Antibody (Clone#OTI2F1)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RIPK1 Antibody (Clone#OTI2F1) |
指标别名 | Cell death protein RIP;Receptor interacting protein 1;RIP;RIP 1;RIP1;RIPK1;RIPK1-Specific |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | RIPK1 |
克隆号 | OTI2F1 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Human recombinant protein fragment corresponding to amino acids 133-422 of human RIPK1(NP_003795) produced in E.coli. |
实际分子量 | 75.8KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | RIPK1,also known as RIP or RIP1,is an enzyme that in humans is encoded by the RIPK1 gene.It is mapped to 6p25.2.RIPK1 is a key signaling molecule in the programmed necrosis pathway,which plays important roles in development,tissue damage response,and antiviral immunity.RIPK1 is known to have function in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).The kinase domain,while important for necroptotic (programmed necrotic) functions,it appears dispensable for other lethal,as well as pro-survival roles.Also,proteolytic processing of RIPk1,through both caspase-dependent and -independent mechanisms,triggers lethality that is dependent on the generation of one or more specific C-terminal cleavage product(s) of RIPk1 upon stress. |
Uniprot ID | Q13546 |
基因名全称 | receptor(TNFRSF)-interacting serine-threonine kinase 1 |
蛋白名全称 | Receptor-interacting serine/threonine-protein kinase 1 |
推荐稀释比 | Western blot (WB) 1:500 |
相关搜索:RIPK1抗体,RIPK1单抗,Anti-RIPK1 Antibody (Clone#OTI2F1)